Provigil Resources

Can it help people who aren't sleepy?

2005-07-13T14:57:00.000-07:00

Does Provigil enhance cognitive performance in people who are not sleep-deprived?

In a double-blind, parallel groups study, 60 healthy student volunteers (29 men and 31 women, aged 19-22 years) were randomly allocated to receive placebo, 100 or 200 mg modafinil. Two hours later, in the early evening, they completed an extensive cognitive battery. The 3 groups did not differ in self-ratings of sleepiness or tiredness before the testing session, and there were no treatment-associated changes in these or in mood ratings during the tests. Modafinil was without effect in several tests of reaction time and attention, but the 200-mg group was faster at simple color naming of dots and performed better than placebo in the Rapid Visual Information Processing test of sustained attention. Modafinil was without effect on spatial working memory, but the 100-mg group performed better in the backward part of the digit span test. Modafinil was without effect on verbal short-term memory (story recall), but 100 mg improved digit span forward, and both doses improved pattern recognition, although this was accompanied by a slowing of response latency in the 200-mg group. There were no significant effects of modafinil compared with placebo in tests of long-term memory, executive function, visuospatial and constructional ability, or category fluency. These results suggest that the benefits of modafinil are not clearly dose-related, and those from 100 mg are limited to the span of immediate verbal recall and short-term visual recognition memory, which is insufficient for it to be considered as a cognitive enhancer in non-sleep-deprived individuals.

Taking Provigil

2005-06-17T14:34:00.000-07:00

The use of Provigil in combination with alcohol has not been studied. People taking Provigil should avoid alcohol until the matter has been thoroughly studied.

The World Anti-Doping Agency (WADA) included Provigil on its 2004 List of Prohibited Substances and Methods. Olympic athletes as well as professional athletes participating in other sporting events around the world mayl be disciplined if they test positive for modafinil.

2005-06-14T16:31:00.000-07:00

Usually people go through five stages of sleep: 1, 2, 3, 4 and REM (rapid eye movement) sleep. These stages progress cyclically from 1 through REM then begin again with stage 1. A complete sleep cycle takes an average of 90 to 110 minutes. The first sleep cycles each night have relatively short REM sleeps and long periods of deep sleep but later in the night, REM periods lengthen and deep sleep time decreases.

About Provigil

2004-11-18T14:30:00.000-08:00

Provigil information can be found here. This has the potential to become a lifestyle drug. Actually, it already is.

Glossary of Sleep Terms

2004-11-04T13:46:00.000-08:00

This glossary of sleep-related terms can be useful for people interested in the field, or just anyone who wants to learn a little about sleep. And we all sleep, right?

Off-label Provigl use

2004-11-03T10:48:00.000-08:00

I read somewhere that 90% of the prescriptions for modafinil in the United States for for
off-label Provigil use.

Amazing. The drug is "approved" for narcolepsy, but used for other reasons.